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. 2018 Oct 18;26(12):2848–2862. doi: 10.1016/j.ymthe.2018.09.013

Table 2.

Extent of Deamidation (%) at Five AAV8 NG Sites in WT and Six +1 Site Mutants

Amino Acid Identity WT (Average) G58S G58A G264A G386S G386A G515A
N57 81.8 8.4 1.9 89.7 89.7 91.6 93.6
N263 99.3 98.2 98.9 4.8 100.0 94.5 97.2
N385 89.1 96.3 94.8 97.1 13.5 2.5 97.0
N514 85.2 100.0 98.0 98.8 100.0 100.0 2.2
N540 84.5 95.0 92.6 97.9 96.9 86.1 89.5