Table 8.
Correlation of HDAC mRNA expression with overall survival in different TP53 mutation status ovarian cancer patients.
| HDAC | TP53 mutation | cases | HR (95% CI) | P value |
|---|---|---|---|---|
| HDAC1 | yes | 506 | 0.78(0.61-0.99) | 0.0402* |
| no | 94 | 0.76(0.43-1.35) | 0.3472 | |
| HDAC2 | yes | 124 | 1.66(1.09-2.52) | 0.0172* |
| no | 19 | Not available | Not available | |
| HDAC4 | yes | 124 | 0.76(0.51-1.14) | 0.1866 |
| no | 19 | Not available | Not available | |
| HDAC5 | yes | 124 | 1.21(0.8-1.81) | 0.3664 |
| no | 19 | Not available | Not available | |
| HDAC11 | yes | 124 | 1.71(1.14-2.58) | 0.0095* |
| no | 19 | Not available | Not available |
*: P<0.05