Figure 1.
ZD55-IL-24 and DTX exhibited synergistic effects to inhibit DU145 cell viability. (A) DU145 cells were treated with DTX at indicated concentration for up to 4 days. (B) DU145 cells were treated with ZD55-IL-24 at the indicated concentration for up to 4 days. (C) DU145 cells were treated with ZD55-IL-24 or ZD55-EGFP (10 MOI) for up to 4 days. (D) DU145 cells were treated with ZD55-IL-24 (10 MOI) in combination with DTIC (1 ng/ml) for up to 4 days. For comparison, DU145 cells were treated with vehicle (control), ZD55-IL-24 (15 MOI) or DTX (3 ng/ml). Cell viability was detected by MTT assay. *P<0.05, **P<0.01, ***P<0.001.