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Adverse effects of three groups.
| No. (%) | |||||
|---|---|---|---|---|---|
| Adverse effect | Total (n = 674) | Betahistine (n = 13) | Metformin (n = 25) | Placebo (n = 29) | P-value |
| Nausea | 11(16.4) | 0(0) | 5(20.0) | 4(13.8) | 0.6 |
| Extrapyramidal Symptoms | 17(25.4) | 2(15.4) | 5(20.0) | 8(27.6) | |
| Insomnia and agitation | 13(19.4) | 1(7.7) | 5(20.0) | 5(17.2) | |
| Somnolence | 7(10.4) | 1(7.7) | 2(8.0) | 2(6.9) | |
| Headache | 6(9.0) | 2(15.4) | 2(8.0) | 2(6.9) | |
| Dry mouth | 6(9.0) | 0(0) | 2(8.0) | 2(6.9) | |
Fisher's exact test among three groups.
