Table 4.
Diagnostic properties of the different inflammatory markers.
| Test | Threshold values | Se (%) | Sp (%) | PPV (%) | NPV (%) | LR+ | LR- |
|---|---|---|---|---|---|---|---|
| CRPi n = 130 | 4.05 mg/l | 70.59 | 84.21 | 61.54 | 88.89 | 4.47 | 0.35 |
| (52.52–84.90) | (75.30–90.88) | (44.62–76.64) | (80.51–94.54) | (2.79–8.38) | (0.17–0.54) | ||
| Quantitative IL-8 n = 114 | 107 ng/l | 40,62 | 86.59 | 54.17 | 78.89 | 3.03 | 0.69 |
| (23.70–59.36) | (77.26–93.11) | (32.82–74.44) | (69.01–86.79) | (1.54–6.66) | (0.48–0.89) | ||
| Semi-quantitative IL-8 n = 91 | 77.5 ng/l | 48.15 | 92.19 | 72.22 | 80.82 | 6.17 | 0.56 |
| (28.67–68.05) | (82.70–97.41) | (46.52–90.30) | (69.92–89.10) | (2.67–28.44) | (0.36–0.78) | ||
| PCT n = 106 | 0,69 μg/l | 59.26 | 78.48 | 48.48 | 84.93 | 2.75 | 0.52 |
| (38.80–77.61) | (67.80–86.94) | (30.80–66.46) | (74.6–92.23) | (1.61–4.95) | (0.29–0.78) | ||
| IL-6/CRPi n = 126 | 21.7 ng/l−4.05 mg/l | 78.12 | 76.34 | 53.19 | 91,03 | 3.30 | 0.29 |
| (60.03–90.72) | (66.40–84.54) | (38.08–67.89) | (82.38–96.32) | (2.25–5.27) | (0.12–0.49) | ||
| Quantitative IL-8 / CRPi n = 114 | 107 ng/l−4.05 mg/l | 75.00 | 75.31 | 54.55 | 88,41 | 3.04 | 0.33 |
| (56.60–88.54) | (64.47–84.22) | (38.85–69.61) | (78.43–94.86) | (2.01–5.06) | (0.13–0.55) | ||
| Semi–quantitative IL-8 / CRPi n = 91 | 77.5 ng/l−4.05 mg/l | 74.07 | 77.78 | 58,82 | 87,50 | 3.33 | 0.33 |
| (53.72–88.89) | (65.54–87.28) | (40.70–75.35) | (75.93–94.82) | (2.09–6.13) | (0.13–0.57) |
The values in brackets indicate the 95% confidence intervals.
Se, Sensitivity ; Sp, Specificity; PPV, Positive predictive values; NPV, Negative predictive values; LR+, Positive likelihood ratios; LR-, Negative likelihood ratios.