Table 5.
Diagnostic properties of the different inflammatory markers in the certainly infected infants.
| Test | Threshold values | Se (%) | Sp (%) | PPV (%) | NPV (%) | LR+ | LR- |
|---|---|---|---|---|---|---|---|
| CRPi n = 83 | 7.82 mg/l | 66.67 | 89.23 | 63.16 | 90.62 | 6.19 | 0.37 |
| (40.99; 86.66) | (79.06; 95.56) | (38.36; 83.71) | (80.70; 96.48) | (2.86; 13.40) | (0.19; 0.72) | ||
| Quantitative IL-8 n = 69 | 74.13 ng/l | 43.75 | 89.09 | 53.85 | 84.48 | 4.01 | 0.63 |
| (19.75; 70.12) | (77.75; 95.89) | (25.13; 80.78) | (72.58; 92.65) | (1.57; 10.24) | (0.41; 0.98) | ||
| Semi quantitative IL-8 n = 52 | 77.72 ng/l | 53.85 | 95.24 | 77.78 | 86.96 | 11.31 | 0.48 |
| (25.13; 80.78) | (83.84; 99.42) | (39.99; 97.19) | (73.74; 95.06) | (2.67; 47.88) | (0.27; 0.88) | ||
| PCT n = 63 | 1.5 μg/l | 53.85 | 98.04 | 87.5 | 89.29 | 27.46 | 0.47 |
| (25.13; 80.78) | (89.55; 99.95) | (47.35; 99.68) | (78.12; 95.97) | (3.70; 203.91) | (0.26; 0.85) | ||
| IL-6/CRPi n = 79 | 21.4–7.82 mg/l | 75 | 84.13 | 54.55 | 92.98 | 4.72 | 0.3 |
| (47.62; 92.73) | (72.74; 92.12) | (32.21; 75.61) | (83.00; 98.05) | (2.50; 8.92) | (0.13; 0.70) | ||
| Semi quantitative IL-8/CRPi n = 52 | 77.72 ng/l−7.82 mg/l | 69.23 | 88.1 | 64.29 | 90.24 | 5.82 | 0.35 |
| (38.57; 90.91) | (74.37; 96.02) | (35.14; 87.24) | (76.87; 97.28) | (2.37; 14.29) | (0.15; 0.80) |