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. 2018 Nov 23;9:2854. doi: 10.3389/fmicb.2018.02854

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Copyright © 2018 Cordovana, Kostrzewa, Glandorf, Bienia, Ambretti and Pranada.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Detection of the KPC-related peak by the automated algorithm. An internal calibration peak specific to K. pneumoniae is recognized and used for higher precision in peak detection in the window of m/z 11,109 +/-5. The dotted red line corresponds to a multiple of the average noise in the spectrum. It is used as a threshold for the intensity in peak detection. (A) KPC-positive K. pneumoniae strain with peak for the pKpQIL plasmid. (B) KPC-negative strain. In the detection window only noise below the detection threshold can be observed.