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. 2018 Nov 27;9:1363. doi: 10.3389/fphar.2018.01363

Table 1.

Contrast-enhanced ultrasound modes of thyroid nodules.

Pathology Entry pattern
Regression pattern
Contrast pattern
Wash-in earlier Wash-in at the same time Wash-in later Wash-out earlier Wash-out at the same time Wash-out later Concentric Non-concentric
Benign 23 29 7 9 40 10 6 53
Nodular goiter 12 16 7 7 25 3 6 29
Nodular goiter with nodular hyperplasia 4 11 2 11 2 15
Adenoma 7 2 4 5 9
Malignant 9 7 13 17 11 1 22 7
Papillary carcinoma 8 7 12 16 11 21 6
Follicular carcinoma 1 1 1
Metastasis carcinoma 1 1 1
χ2-value 12.607 17.101 38.677
P-value 0.002 <0.001 <0.001