Figure 5.

The surface of SDS22 is segregated by charge. (a) Acidic residues (Asp and Glu) are shown as sticks (left) and are located primarily on the concave and convex surfaces of SDS22 (right; red, negative; blue, positive). (b) Basic residues (Arg and Lys) are shown as sticks (left) and are located on the ‘top’ and ‘bottom’ of SDS22 (right). Ten basic residues from LRR2–LRR8 define a particularly distinctive basic patch that we defined as the basic ridge.