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The PPV of NIPT for fetal SCAs with different prenatal diagnosis indications
| Sex chromosomal aneuploidies | Prenatal diagnostic indications | ||
|---|---|---|---|
| True positive rate(%)(Amniocentesis/ NIPT) | |||
| Types | advanced maternal age | others | serological screening high/ critical risk value |
| 45,X | 45.45(5/11) | 25.00(2/8) | – |
| 47,XXY | 72.73(8/11) | 100.00(1/1) | – |
| 47,XYY | 50.00 (1/2) | — (0/0) | – |
| 47,XXX | 100.00(7/7) | 100.00(2/2) | 0.00(0/1) |
| Total | 67.74(21/31) | 45.45(5/11) | 0.00(0/1) |
