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. 2018 Dec 4;10:150. doi: 10.1186/s13148-018-0578-9

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Aberrant methylation of four iDMRs within the IGF2/H19 domain in tumors. Hypermethylation of the H19-promoter and H19-DMR were found in only a few samples. However, hypomethylation of IGF2-DMRs, especially DMR0, was comparatively overrepresented among iDMRs (*p = 0.0061, **p < 0.0001, χ² test)