Table 1.

List of host chloroplast and chloroplast-related factors and viral protein interactions involved in Synthesis of viral genomic RNA [(+)ssRNA] plant virus replication.

Host factors	Viral proteins/RNA	Viruses	Identified function in replication	Reference
NbRabG3f	–		VRC membrane trafficking	Huang et al., 2016
ChlPGK	RNA 3′UTR	potexvirus, BaMV	VRC membrane trafficking	Cheng et al., 2013
Hsp90	Viral polymerase RdRp/RNA3′UTR		VRC assembly	Huang et al., 2017
CA	–		initiation of RNA synthesis	Chen et al., 2017
GAPDH	RNA/satRNA 3′UTR		inhibition of the minus strand RNA synthesis (negative regulation)	Huang et al., 2017
PMTS1	Viral RdRp		an inhibitory effect on RdRp activity	Cheng et al., 2009
	VRC		targeting VRC to chloroplasts
GSTU4	RNA 3′UTR		activation of minus-strand RNA synthesis	Chen et al., 2013
			a role in the antioxidation process	Huang et al., 2017
XRN4	VRC		enhancement of the accumulation of virus	Huang et al., 2017
Syp71	chloroplast- bound 6K2 complex	potyvirus, TuMV	assembly of VRC; mediation in the fusion of vesicles with chloroplast	Wei et al., 2013
Chloroplast membrane lipids	TGB2	pomovirus, PMTV	VRC membrane trafficking and assembly	Cowan et al., 2012
NbPsbO1	6K2	potyvirus, TVBMV, PVY	positive regulation of RNA synthesis	Geng et al., 2017
ATP- synthase β subunit	TGB1	potexvirus, AltMV	VRC assembly	Nam et al., 2012
ATP- synthase β subunit	–	tymovirus, ToBMV	VRC assembly	Megias et al., 2018
RNA polymerase beta-subunit	-		unknown
eEF1a	RNA 3′UTR	potyvirus, TuMV	role unknown, the colocalization with 6K	Hyodo and Okuno, 2014
		potexvirus, BaMV	inhibition of (−)RNA synthesis	Huang et al., 2017