Table 5.
Effect size of AST/ALT on baPWV in prespecified and exploratory subgroups
| Characteristic | No of participants | Effect size(95%CI) | P for interaction |
|---|---|---|---|
| Age (year) | 0.001 | ||
| ≤ 60 | 98 | 15.6 (6.3, 25.0) | |
| > 60 | 531 | −0.8 (−5.7, 4.1) | |
| Sex | 0.32 | ||
| male | 372 | 5.5 (−0.5, 11.5) | |
| female | 274 | 1.3 (−4.9, 7.6) | |
| 5.4 (−2.7, 13.5)* | |||
| Current smoking | 0.83 | ||
| no | 517 | 3.0 (−1.6, 7.5) | |
| yes | 129 | 1.5 (−11.1, 14.2) | |
| Ex-Smoking | 0.88 | ||
| no | 346 | 2.6 (−3.2, 8.4) | |
| yes | 300 | 3.2 (−3.1, 9.5) | |
| Regular Exercise (> 1 week) | 0.08 | ||
| no | 488 | 0.2 (−4.6, 5.1) | |
| yes | 146 | 8.8 (0.1, 17.5) | |
| Alcohol consumption | 0.54 | ||
| ≤ 40 (g/week) | 419 | 1.1 (−4.1, 6.3) | |
| 40–140 | 107 | 8.1 (−2.8, 18.9) | |
| 140–280 | 57 | 6.3 (−14.7, 27.4) | |
| > 280 | 58 | 8.8 (−8.0, 25.7) | |
| BMI | 0.54 | ||
| < 18.5 | 36 | 11.7 (−10.8, 34.1) | |
| > =18.5, < 23 | 386 | 5.8 (0.4, 11.2) | |
| > =23 | 224 | 1.6 (−6.2, 9.5) | |
| Hypertension | 0.90 | ||
| no | 585 | 3.3 (−1.4, 7.9) | |
| yes | 61 | 2.2 (−14.3, 18.7) | |
| Uric acid (tertile) | 032 | ||
| low | 298 | 3.9 (−3.7, 11.5) | |
| middle | 308 | −3.8 (−12.9, 5.2) | |
| high | 306 | 4.5 (−5.4, 14.4) |
Note 1:Above model adjusted for sex; age; BMI; SBP; DBP; γ-GTP; fasting glucose; uric acid; TC; TG; HDL-C; LDL; smoking status (current and ex-); excise; e-GFR; ABIM; alcoholic consumption
Note 2:In each case, the model is not adjusted for the stratification variable
Note 3: * adjusted menopausal status + sex; age; BMI; SBP; DBP; γ-GTP; fasting glucose; uric acid; TC; TG; HDL-C; LDL; smoking status (current and ex-); excise; e-GFR; ABIM; alcoholic consumption