Scheme 1.
Synthesis of enantiomeric (E)-3-(2′,5′-dimethylphenyl)hex-4-enoic acids [(S)-3 and (R)-3]. Reactions and conditions: (i) CH3C(OEt)3, C2H5COOH, 138 °C and (ii) NaOH, EtOH, reflux.
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.