Figure 2.
Effects of Tiansi Liquid on TRP–KYN metabolites. Effects of Tiansi Liquid treatment on TRP (A), KYN (B), KYN/TRP ratio (C), KYNA (D) and QUIN (E). Effect of Tiansi Liquid treatment on the expression of TDO mRNA in the liver and IDO mRNA in the hippocampus (F). TRP, KYN, KYNA and QUIN denote tryptophan, kynurenine, kynurenic acid and quinoline, respectively; TDO denotes tryptophan-2,3-dioxygenase; and IDO denotes indoleamine 2,3-dioxygenase. Ten rats in each group. Statistical analyses were performed using one-way ANOVA and Tukey—Kramer post hoc comparisons. # p < 0.05, vs. control group; * p < 0.05, vs. model group.