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Binding pocket on CD4 surface (A) and compounds exhibited varying extents of inhibition of anti-human CD4 antibody binding to CD4 (B). The docking models of NSC119915 and CD4 receptor (C) and interaction of NSC119915 and CD4 (D). NSC119915 displayed dose-dependent inhibition (E) while not showing any cytotoxicity (F). * p value < 0.05, ** p value < 0.005.
