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. 2018 Oct 26;23(11):2783. doi: 10.3390/molecules23112783
ACD Anemia of chronic disease
ALK Anaplastic lymphoma kinase
AR Adrenergic receptor
Bcr-Abl Break point cluster-Abelson
Btk Bruton’s tyrosine kinasel
CD Crohn’s disease
CDK Cyclin-dependent kinase
CHK Checkpoint kinase
DCE 1,2-Dichloroethane
DDQ 2,3-Dicyano-5,6-dichlorobenzoquinone
DFT Density functional theory
DMPK Drug metabolism and pharmacokinetics
DMPU 1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone
DMSO Dimethyl sulfoxide
EGFR Epidermal growth factor receptor
ER Endoplasmic reticulum
ERK Extracellular signal-regulated kinase
EZH Enhancer of zeste homologue
FBLD Fragment-based lead discovery
FDA Food and drug administration
FGFR Fibroblast growth factor receptor
FRET Forster resonance energy transfer
FLT3 Fms-like tyrosine kinase 3
FtsZ Filamentous temperature-sensitive protein Z
GK Glucokinase
GPR G-protein coupled receptor
GR Glucocorticoid receptor
GRAs Glucagon receptor antagonists
GRK G protein-coupled receptor kinase
GSK3β Glycogen synthase kinase 3 betas
hCAs Human carbonic anhydrases
HDACs Histone deacetylases
hEGR Human ether-a-go-go related gene
hFOB Human fetal osteoblasts
HFIP Hexafluoroisopropanol
HT Hydroxytryptamine
HTS High-throughput screening
HUVEC Human umbilical vein endothelial cells
IDO Indoleamine-pyrrole 2,3-dioxygenase
IKKβ Inhibitor of nuclear factor kappa-B kinase betan
JAK Janus kinase
LE Excellent ligand
LPS Lipopolysaccharide
LRRK Leucine-rich repeat kinase
MA Molecular sieves
MAC Membrane attack complex
MBA Methoxybenzamide
MCHR Melanin-concentrating hormone receptor
MIC Minimum inhibitory concentration
NMT N-myristoyltransferase
NMR Nuclear magnetic resonance
NOD Nucleotide-binding oligomerization domain-containing protein
NSCLC Non-small cell lung cancer
OGTT Oral glucose tolerance test
OPG Osteoprotegerin
PAD Protein arginine deiminase
PD Pharmacodynamic
PDGFRβ Platelet-derived growth factor receptor betan
PDK Phosphoinositide-dependent kinase
PEC Posterior eye cup
PI3Kδ Phosphoinositide 3-kinase deltae
PIFA [Bis-(trifluoroacetoxy)iodo]benzene
PK Pharmacokinetic
PKC Protein kinase C
PLK4 Polo-like kinase 4
RET Rearranged during transfection
RIP Receptor-interacting protein
ROCK Rho-associated coiled-coil kinase
SAHA Suberoylanilide hydroxamic acid
SAR Structure-activity relationship
SCW Streptococcal cell wall
SEDRs Selective estrogen receptor degraders
SGRMs Selective glucocorticoid receptor modulators
SNAr Nucleophilic aromatic substitution
TA Transactivation
TAT Tyrosine aminotransferase
TGI Tumor growth inhibition
TNFα Tumor necrosis factor-alphas
TTK Tyrosine threonine kinase
TR Transrepression
TRPA Transient receptor potential ankyrin-repeat
UC Ulcerative colitis
ULK Unc-51-like kinase
USP Ubiquitin specific protease
VEGFR Vascular endothelial growth factor receptor