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. 2018 Oct 29;41(1):213–223. doi: 10.3892/or.2018.6828

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Copyright: © Yu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — UDCA inhibited cell proliferation, motility ability and induced morphological changes in A375 cells. (A) Effect of UDCA on the survival rate of the M14 cells and A375 cells using MTT assay. *P<0.05 and **P<0.01 as compared with control group. (B) Morphological changes in A375 cell line treated with UDCA at different concentrations for 48 h using fluorescence microscopy with AO/EB and Hoechst 33258 staining. (C) Effects of UDCA on the motility of A375 cells. UDCA, ursodeoxycholic acid; AO/EB, acridine orange/ethidium bromide.