Figure 1.

Effects of oral treatment of Pentaherbs formula (PHF) on airway remodeling of the allergic asthmatic mice. (A–E) Representative H&E staining (100×) and (F–O) PAS staining (100× & 400×), which denoted the smooth muscle hypertrophy and the goblet cell hyperplasia of the lung, respectively, were performed on day 30 (n = 3–4). Black arrows depict the smooth muscle thickness and red arrows denote the distribution of the mucus-secreting goblet cells. PBS: healthy control; OVA: ovalbumin (OVA)-induced allergic asthmatic control; PHF14: mice with 14-day PHF treatment; PHF8: mice with 8-day PHF treatment; Dex: dexamethasone positive control.