Table I.
Correlations of the clinicopathological features with p-Src and VEGF-A expression in patients with osteosarcoma.
p-Src | VEGF-A | |||||||
---|---|---|---|---|---|---|---|---|
Clinical characteristics | Group | n | Positive | Negative | P-valuea | Positive | Negative | P-valuea |
Sex | Male | 13 | 6 | 7 | 1 | 7 | 6 | 0.688 |
Female | 13 | 7 | 6 | 9 | 4 | |||
Age (years) | <20 | 19 | 8 | 11 | 0.378 | 10 | 9 | 0.19 |
≥20 | 7 | 5 | 2 | 6 | 1 | |||
Tumor location | Femur | 14 | 5 | 9 | 0.215 | 7 | 7 | 0.397 |
Tibia | 10 | 6 | 4 | 7 | 3 | |||
Other | 2 | 2 | 0 | 2 | 0 | |||
Histological type | Osteoblastic | 12 | 7 | 5 | 0.876 | 10 | 2 | 0.185 |
Chondroblastic | 5 | 2 | 3 | 2 | 3 | |||
Fibroblastic | 2 | 1 | 1 | 1 | 1 | |||
Other | 7 | 3 | 4 | 3 | 4 | |||
Enneking stage | IIA | 3 | 0 | 3 | 0.029 | 1 | 2 | 0.05 |
IIB | 13 | 5 | 8 | 6 | 7 | |||
III | 10 | 8 | 2 | 9 | 1 | |||
Tumor size (cm) | <8 | 15 | 9 | 6 | 0.428 | 11 | 4 | 0.228 |
≥8 | 11 | 4 | 7 | 5 | 6 | |||
Recurrence | Yes | 8 | 5 | 3 | 0.673 | 6 | 2 | 0.42 |
No | 18 | 8 | 10 | 10 | 8 | |||
Metastasis | Yes | 10 | 8 | 2 | 0.041 | 9 | 1 | 0.037 |
No | 16 | 5 | 11 | 7 | 9 |
Fisher's exact test.