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Graphical view of the enhanced demons force (intensity = strength) in two volunteer subjects: the original demons force (left), the difference image with voxel intensity difference (VID) (middle), and the enhanced force (right). The voxel with non‐zero force will be deformed in the direction of the voxel intensity gradient and a Gaussian filter is applied to the displacement vector field in each iteration to regulate the anatomy integrity throughout the optimization.
