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. 2018 Nov 29;11:8481–8490. doi: 10.2147/OTT.S178916

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© 2018 Miao et al. This work is published and licensed by Dove Medical Press Limited

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Expression of SOX18 in CRC tissues and cell lines.

Notes: (A) mRNA levels of SOX18 in 60 paired CRC samples and normal non-tumor tissues, as assessed by qRT-PCR. (B) Protein expression of SOX18 in CRC tissues and normal tissues determined by immunohistochemistry. Magnification: 200×. (C) Survival rates of patients with CRC with high and low SOX18 levels by Kaplan–Meier survival analysis. (D) mRNA levels of SOX18 in human colon epithelial cells (NCM460) and CRC cells (HT-29, HCT-116, SW620, and OUMS23) detected by qRT-PCR. (E) Protein levels of SOX18 in human colon epithelial cells (NCM460) and CRC cells (HT-29, HCT-116, SW620, and OUMS23) detected by Western blotting. Data are presented as mean ± SD. **P<0.01, ***P<0.001 vs NCM460 cell line.

Abbreviations: CRC, colorectal cancer; SOX18, region, sex determining region Y (SRY)-box 18; qRT-PCR, quantitative real-time PCR.