Table 1.

Association between clinicopathological features and SOX18 expression in 60 patients with CRC

Characteristics	Number of patients	SOX18 Low expression (≤medium)	SOX18 High expression (≥medium)	P-value
Number	60	34	26
Ages (years)				0.660
<60	25	15	10
≥60	35	19	16
Gender				0.944
Female	32	18	14
Male	28	16	12
Location				0.651
Left	32	19	13
Right	28	15	13
Tumor size				0.944
≤3	28	16	12
>3	32	18	14
AJCC stage				<0.001
I	21	18	3
II	14	10	4
III	21	5	16
IV	4	1	3
Differentiation				0.472
Well	18	10	8
Moderately	27	15	12
Poorly	15	9	6
Vascular invasion				0.002
Yes	28	10	18
No	32	24	8
Depth of invasion				0.036
T1	8	6	2
T2	11	8	3
T3	24	13	11
T4	17	7	10
Lymph node metastasis				0.001
N0	26	21	5
N1	20	10	10
N2	14	3	11
Distant metastasis				0.015
M0	46	30	16
M1	14	4	10

Abbreviations: AJCC stage, American Joint Committee on Cancer; CRC, colorectal cancer; SOX18, sex determining region Y (SRY)-box 18.