Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Nov 29;11:8543–8553. doi: 10.2147/OTT.S175578

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2018 Li et al. This work is published and licensed by Dove Medical Press Limited

The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

PMC Copyright notice

Vandetanib induced growth inhibition, apoptosis, and cell cycle arrest.

Notes: (A) MDA-MB-231 apoptosis under vandetanib treatment was measured by flow cytometry with Annexin V/PI staining. (B) MDA-MB-231 cell cycle analysis upon vandetanib treatment by flow cytometry with PI staining. (C) MDA-MB-231 growth inhibition, quantification of apoptosis and quantification of cell cycle induced by vandetanib. (D) MCF-7 apoptosis under vandetanib treatment was measured by flow cytometry with Annexin V/PI staining. (E) MCF-7 cell cycle analysis upon vandetanib treatment by flow cytometry with PI staining. (F) MCF-7 growth inhibition, quantification of apoptosis, and quantification of cell cycle induced by vandetanib. *P<0.05 (compared with control) or ^#P<0.05 (compared with NC) was considered significant.

Abbreviations: NC, negative control; PI, propidium iodide.

Vandetanib induced growth inhibition, apoptosis, and cell cycle arrest.

Notes: (A) MDA-MB-231 apoptosis under vandetanib treatment was measured by flow cytometry with Annexin V/PI staining. (B) MDA-MB-231 cell cycle analysis upon vandetanib treatment by flow cytometry with PI staining. (C) MDA-MB-231 growth inhibition, quantification of apoptosis and quantification of cell cycle induced by vandetanib. (D) MCF-7 apoptosis under vandetanib treatment was measured by flow cytometry with Annexin V/PI staining. (E) MCF-7 cell cycle analysis upon vandetanib treatment by flow cytometry with PI staining. (F) MCF-7 growth inhibition, quantification of apoptosis, and quantification of cell cycle induced by vandetanib. *P<0.05 (compared with control) or ^#P<0.05 (compared with NC) was considered significant.

Abbreviations: NC, negative control; PI, propidium iodide.