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. 2018 Nov 29;11:8529–8541. doi: 10.2147/OTT.S188209

Table 4.

Half-life of apatinib in HCC tissues injected with apatinib formulations

Apatinib formulations Half-life of apatinib in HCC tissues (t1/2 value; hours)

Apa-Sol 16.55±1.66
Apa-Cyc 18.65±2.07
Apa-Gel 99.16±7.67

Notes: Data are presented as mean±SD.

Abbreviations: Apa-Cyc, apatinib–cyclodextrin inclusion complex; Apa-Sol, apatinib solution; HCC, hepatocellular carcinoma.