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. 2018 Nov 29;11:8517–8528. doi: 10.2147/OTT.S183887

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© 2018 Ma et al. This work is published and licensed by Dove Medical Press Limited

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In vivo NIR fluorescence and thermal imaging.

Notes: (A) Fluorescence signal was obtained in tumor sites at 10 minutes and 24 hours after intravenous administration of free ICG, IBA NPs and RGD-IBA NPs. (B) The quantitative analysis of fluorescence intensity in tumor sites at 0 minute, 10 minutes, 12 hours, 24 hours and 36 hours after intravenous administration of free ICG, IBA NPs and RGD-IBA NPs. (C) The tumor temperature change of tumor-bearing mice after 24 hours of intravenous injection of saline, IBA NPs and RGD-IBA NPs and durations NIR irradiation (808 nm, 1 W/cm²). (D) The corresponding thermal images of tumor-bearing mice before and after 5 minutes of irradiation.

Abbreviations: ART, artemisinin; FL, fluorescence; ICG, indocyanine green; NIR, near infrared; NPs, nanoparticles; RGD, arginine-glycine-aspartic acid.