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. 2018 Nov 29;11:8517–8528. doi: 10.2147/OTT.S183887

Figure 9.

Figure 9

In vivo anticancer.

Notes: (A) The tumor growth profile and (B) body weight of KB tumor-bearing mice after intravenous injection of saline, ART, IBA NPs and RGD-IBA NPs with or without 5 minutes of NIR irradiation (808 nm, 1 W/cm2). The RGD-IBA NPs + NIR group compared with other groups, **P<0.01. (C) HE-stained tissue sections of major organs, including the heart, liver, spleen, lung and kidney from mice treated with saline (control) or RGD-IBA NPs at day 30 (magnification: 100×).

Abbreviations: ART, artemisinin; HE, hematoxylin and eosin; ICG, indocyanine green; NIR, near infrared; NPs, nanoparticles; RGD, arginine-glycine-aspartic acid.