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. 2018 Jul;3(7):635–643. doi: 10.1016/j.bpsc.2017.11.013

Table 3.

Prediction of Polygenic Risk Score for Attention-Deficit/Hyperactivity Disorder on Target and Control Phenotypes

Target or Control Phenotype p pT R2 (%) SNPs, n
Body Mass Index 4.5 × 10−129 .440 .448 69,995
Verbal-Numerical Reasoning 4.5 × 10−36 .418 .379 67,558
Alcohol Intake Frequency 8.1 × 10−29 .231 .093 44,307
Risk-Taking 9.3 × 10−25 .291 .115 52,388
Neuroticism 2.2 × 10−24 .139 .092 30,306
Tobacco Use 4.2 × 10−21 .485 .333 74,809
Height 8.7 × 10−20 .081 .030 20,147
Depressive Disorder 2.2 × 10−13 .033 .112 10,158
Age, Years 5.8 × 10−9 .177 .026 36,443
Alcohol Dependency 4.5 × 10−6 .175 .208 36,101
Anxiety Disorder 2.8 × 10−4 .116 .062 26,355
Visual Acuity .005 .001 .029 792
Bipolar Disorder .007 .117 .037 26,551
Hand Grip Strength .024 .494 .002 75,689
Menstruation at Assessment .115 .051 .025 14,128
No. of Cancers .127 .131 .002 28,929
Schizophrenia .162 .257 .053 47,870
Year of Assessment .159 .036 .001 10,871
Sex of Child .234 .010 .062 4085

Significance threshold set at p < 2.1 × 10−4.

SNP, single nucleotide polymorphism.