Table 3.
Per-patient sensitivity and specificity for disease presence and extent against the consensus reference standard for patient groups combined
|
Sensitivity |
Specificity |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Number of disease positive* | MRE | Ultrasound | Difference | p value | Number disease negative* | MRE | Ultrasound | Difference | p value | |
| Small bowel disease extent† | 233 | 80% (72 to 86) | 70% (62 to 78) | 10% (1 to 18) | 0·027 | 51 | 95% (85 to 98) | 81% (64 to 91) | 14% (1 to 27) | 0·039 |
| Small bowel disease presence | 233 | 97% (91 to 99) | 92% (84 to 96) | 5% (1 to 9) | 0·025 | 51 | 96% (86 to 99) | 84% (65 to 94) | 12% (0 to 25) | 0·054 |
| Colonic disease extent† | 129 | 22% (14 to 32) | 17% (10 to 27) | 5% (−5 to 15) | 0·332 | 155 | 93% (87 to 97) | 93% (87 to 97) | 0% (−5 to 5) | 1·000 |
| Colonic disease presence | 129 | 64% (50 to 75) | 73% (59 to 83) | −9% (−23 to 5) | 0·202 | 155 | 96% (90 to 98) | 96% (90 to 98) | 0% (−3 to 3) | 1·000 |
| Small bowel and colonic disease extent† | 270 | 44% (36 to 54) | 29% (21 to 38) | 16% (6 to 25) | 0·002 | 14 | 80% (42 to 96) | 61% (23 to 89) | 19% (−20 to 59) | 0·337 |
| Small bowel and colonic disease presence‡ | 270 | 78% (70 to 85) | 71% (62 to 79) | 7% (−2 to 15) | 0·117 | 14 | 80% (42 to 96) | 61% (23 to 89) | 19% (−20 to 59) | 0·335 |
Data are n, % (95% CI), or p value. MRE=magnetic resonance enterography.
Patients by consensus reference standard.
Agreement with reference standard for disease presence and segmental location.
Agreement with reference standard for disease presence (patients with disease in the small bowel, colon, or both).