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. 2018 Dec 4;13(12):e0208067. doi: 10.1371/journal.pone.0208067

Fig 3. Anti-HBsAg IgG titers in immunized mice.

Fig 3

BALB/c mice (n = 10/group) were immunized i.m. with HBsAg (2 μg) with or without adjuvant on days 0 and 21. Animals were bled on Day 20 (Panel A) and 28 (Panel B) with serum analyzed for anti-HBsAg IgG Abs by ELISA. Grouped data is presented as geometric mean titer (GMT) + 95% Confidence Interval (CI). *: p<0.05 & ****: p<0.0001 for various groups receiving adjuvanted formulations when compared to unadjuvanted control group by one-way ANOVA followed by Dunnett's multiple comparisons test.