Table 2.
Cytokine production by luteal immune cell microbead fractions under basal culture conditions
| CD11b-enriched fraction | CD16-enriched fraction | |||
|---|---|---|---|---|
| Cytokine/chemokine/growth factor | Mid-late stage basal | Late/menses basal | Mid-late stage basal | Late/menses basal |
| MCP-1/CCL2 | 122 ± 53* | 972 ± 483** | 37 ± 21 | 20 ± 4 |
| MIP-1α/CCL3 | 30 ± 6a | 156 ± 59b | ND | ND |
| MIP-1β/CCL4 | ND | 48 ± 21 | ND | ND |
| MDC/CCL22 | NDa | 1073 ± 579b | ND | ND |
| IL-8/CXCL8 | 21 ± 6 | 489 ± 247 | ND* | 8 ± 1** |
| IP-10/CXCL10 | ND | ND | ND | ND |
| IFNγ/IFNG | ND | ND | ND | ND |
| IL-1β/IL1B | ND | 6 ± 1 | ND | ND |
| IL6 | ND | 23 ± 15 | ND | ND |
| MIF | ND | 40 ± 18 | ND | 10 ± 1 |
| TNFα/TNF | ND | ND | ND | ND |
| Total number detected each fraction | 3 | 8 | 1 | 3 |
Mean ± SEM(pg/ml).
ND = nondetectable; see Supplemental Table S3 for limits of detection for each assay.
Different letters indicate significant differences within marker for each cytokine between luteal stage; Asterisks indicate trend (P < 0.07) toward difference within marker between luteal stage.