Table 1.
Baseline patient characteristics stratified by ACAOS revascularization
| All patients (n = 103) | No Revasc (n = 83) | Revasc (n = 20) | P-value | |
|---|---|---|---|---|
| Age, years, mean ± SD | 52 ± 17 | 52 ± 17 | 51 ± 15 | 0.93 |
| Follow-up, years, median (IQR) | 5.8 (3.8–7.8) | 5.6 (3.4–7.8) | 6.4 (5.3–7.5) | 0.48 |
| Male, n (%) | 65 (63%) | 53 (64%) | 12 (60%) | 0.75 |
| Diabetes mellitus, n (%) | 19 (19%) | 17 (20%) | 2 (10%) | 0.28 |
| Hyperlipidaemia, n (%) | 51 (50%) | 37 (45%) | 14 (70%) | 0.04 |
| Hypertension, n (%) | 47 (46%) | 35 (42%) | 12 (60%) | 0.15 |
| Current or prior smoker, n (%) | 31 (30%) | 23 (28%) | 8 (26%) | 0.71 |
| Family history early CAD, n (%) | 22 (21%) | 15 (18%) | 7 (35%) | 0.10 |
| Known CAD, n (%) | 7 (7%) | 3 (4%) | 4 (20%) | 0.009 |
| ACAOS known before CTA, n (%) | 57 (55%) | 40 (48%) | 17 (85%) | 0.003 |
| Prior cardiac testing, n (%) | ||||
| Invasive angiography | 45 (44%) | 29 (35%) | 16 (80%) | 0.001 |
| Myocardial perfusion imaging | 42 (41%) | 31 (37%) | 11 (55%) | 0.15 |
| Exercise treadmill test | 19 (18%) | 15 (18%) | 4 (20%) | 0.60 |
| Cardiac MRI (rest only) | 10 (10%) | 9 (11%) | 1 (5%) | 0.30 |
| Stress echocardiogram | 4 (4%) | 2 (2%) | 2 (10%) | 0.19 |
| Stress MRI | 1 (1%) | 1 (1%) | 0 (0%) | 0.53 |
| Any ischaemia on prior testinga | 28/53 (53%) | 19/40 (48%) | 9/13 (69%) | 0.17 |
| Reason for initial evaluation + CTAb | ||||
| Chest pain | 62 (60%) | 48 (58%) | 14 (70%) | 0.32 |
| Dyspnoea | 18 (17%) | 15 (18%) | 3 (15%) | 0.75 |
| Asymptomatic | 18 (17%) | 17 (20%) | 1 (5%) | 0.10 |
| Preoperative evaluation | 13 (13%) | 11 (13%) | 2 (10%) | 0.69 |
| Light-headedness/syncope | 6 (6%) | 5 (6%) | 1 (5%) | 0.86 |
| Research | 5 (5%) | 5 (6%) | 0 (0%) | 0.26 |
| Palpitations/arrhythmia | 4 (4%) | 4 (5%) | 0 (0%) | 0.31 |
| Aborted SCD | 4 (4%) | 1 (1%) | 3 (15%) | 0.004 |
| CV symptomc | 12 (12%) | 14 (15%) | 6 (50%) | 0.004 |
ACAOS, anomalous coronary artery arising from the opposite sinus; CAD, coronary artery disease; CTA, computed tomographic angiography; MRI, magnetic resonance imaging. Revasc, revascularization of ACAOS.
aAmong patients who underwent prior ischaemic testing.
bNote: % do not sum to 100% as some patients had multiple indications for initial evaluation + CTA.
cAborted SCD, or any typical chest pain, presyncope, or syncope provoked by exertion.