Table 3.
Myocardial flow parameters in territories with and without stress-induced perfusion defects (PD) during PET/CT
| Region with PD (R1) | Region without PD and stenosis ≥50% (R2) | P-values (R2 vs. R1) | Region without both PD and stenosis ≥50% (R3) | P-values (R3 vs. R1) | P-values (R3 vs. R2) | |
|---|---|---|---|---|---|---|
| Regional flow | ||||||
| MBF rest | 0.71 (0.67, 0.80) | 0.76 (0.65, 0.90) | 0.202 | 0.75 (0.68, 0.81) | 0.264 | 0.844 |
| MBF stress | 1.44 (1.23, 1.72) | 1.53 (1.38, 2.04) | 0.119 | 1.60 (1.37, 1.82) | 0.202 | 0.782 |
| MFR | 1.97 (1.71, 2.36) | 2.02 (1.92, 2.41) | 0.360 | 2.23 (1.76, 2.37) | 0.505 | 0.757 |
| Longitudinal flow | ||||||
| MBF at rest | ||||||
| Mid-LV segment | 0.90 (0.76, 0.99) | 0.92 (0.77, 1.02) | 0.594 | 0.90 (0.82, 0.99) | 0.416 | 0.762 |
| Mid-distal segment | 0.89 (0.78, 0.97) | 0.86 (0.72, 0.97) | 0.877 | 0.88 (0.78, 1.00) | 0.436 | 0.537 |
| Gradient | −0.01 (−0.05, 0.02) | −0.03 (−0.04, 0.02) | 0.412 | −0.03 (−0.06, −0.00) | 0.966 | 0.424 |
| MBF during stress | ||||||
| Mid-LV segment | 1.87 (1.61, 2.00) | 1.89 (1.80, 1.97) | 0.283 | 1.94 (1.84, 2.05) | 0.322 | 0.913 |
| Mid-distal segment | 1.57 (1.24, 1.84) | 1.23 (1.11, 1.86) | 0.755 | 1.78 (1.48, 2.00) | 0.192 | 0.142 |
| Gradient | −0.17 (−0.29, −0.11) | −0.46 (−0.70, −0.10) | 0.013 | −0.15 (−0.25, −0.09) | 0.333 | 0.002 |
| ΔGradient | −0.19 (−0.26, −0.11) | −0.41 (−0.67, −0.12) | 0.018 | −0.13 (−0.22, −0.07) | 0.285 | 0.002 |
| CVR at rest | ||||||
| Mid-LV segment | 114 (89, 135) | 98 (84, 129) | 0.610 | 97 (86, 126) | 0.496 | 0.849 |
| Mid-distal segment | 113 (90, 133) | 113 (90, 132) | 0.873 | 105 (85, 133) | 0.615 | 0.714 |
| Gradient | 0.63 (−2.79, 6.15) | 4.86 (1.24, 8.57) | 0.200 | 3.93 (0.00, 7.92) | 0.490 | 0.482 |
| CVR during stress | ||||||
| Mid-LV segment | 44 (43, 53) | 45 (40, 49) | 0.219 | 43 (41, 45) | 0.206 | 0.945 |
| Mid-distal segment | 53 (47, 65) | 66 (45, 75) | 0.237 | 47 (44, 59) | 0.150 | 0.014 |
| Gradient | 3.93 (3.13, 10.83) | 20.56 (1.48, 28.11) | 0.011 | 3.96 (2.23, 6.83) | 0.390 | 0.001 |
| ΔCVR gradient | 5.00 (2.20, 7.60) | 9.49 (1.21, 20.58) | 0.051 | 2.00 (−3.96, 4.37) | 0.149 | 0.003 |
Values are median (Q1, Q3).
Region 1 (R1), stress-induced perfusion defect (PD); Region 2 (R2), no stress-induced perfusion defect and stenosis ≥50%; Region 3 (R3), no stress-induced perfusion defect without stenosis ≥50%; MBF, myocardial blood flow (mL/g/min); MFR, myocardial flow reserve; CVR, coronary vascular resistance (mmHg/mL/g/min).
P-values according to Mann–Whitney U test for independent samples.