Table 2.

Genes involved in DNA damage repair. Ratio of expression of genes involved in DNA damage repair pathway in P0 and P7 Lhx8-/- compared to wild-type ovaries (n = 3 per genotype).

P0			P7
Gene	Fold change	P value	Gene	Fold change	P value
Brca2	–1.77	0.021	Apex1	–2.16	0.031
Chek1	–2.37	0.003	Brca1	–1.82	0.030
Ercc1	–2.58	0.001	Brca2	–2.89	0.013
Fancc	–2.74	0.018	Chaf1a	–3.03	0.016
Gadd45a	–1.70	0.007	Chek1	–5.75	0.032
Gtf2h2	–2.00	0.011	Dclre1a	–2.02	0.001
H2afx	–1.51	0.037	Ercc1	–1.41	0.096
Lig1	–1.67	0.032	Exo1	–3.55	0.012
Mgmt	–3.60	0.007	Fancc	–1.78	0.001
Mlh3	–2.44	0.015	Gtf2h1	–1.59	0.021
Msh2	–2.25	0.001	Gtf2h2	–2.09	0.007
Msh3	–1.94	0.014	Hus1	–2.10	0.021
Ogg1	–2.26	<0.001	Lig1	–1.65	0.027
Parp1	–2.03	0.000	Mbd4	–1.43	0.024
Parp2	–2.25	0.005	Mgmt	–3.38	0.021
Pinx1	–3.38	0.006	Mif	–2.33	0.020
Pold1	–1.72	0.016	Msh3	–1.40	0.024
Pold3	–2.29	0.026	Mutyh	–2.33	0.005
Rad1	–2.19	0.011	Nthl1	–2.34	0.001
Rad18	–1.78	0.009	Pinx1	–3.98	<0.001
Rad21	–1.75	0.026	Pms1	–1.63	0.015
Rad23a	–1.94	0.001	Pold1	–2.58	0.006
Rad51c	–2.00	0.015	Pold3	–2.80	0.004
Rad9	–2.10	0.012	Pole	–2.59	0.019
Rad9b	–1.58	0.047	Polk	–1.64	0.011
Rbbp4	–1.76	0.001	Rad1	–2.58	0.011
Smc1a	–1.34	0.029	Rad17	–1.75	0.019
Smc3	–1.55	0.021	Rad18	–2.07	0.002
Terf1	–2.09	0.027	Rad51l1	–1.67	0.004
Trp53	–1.93	<0.001	Srd5a2	22.60	0.001
Xrcc1	–3.08	<0.001	Tdg	–1.19	0.024
Xrcc3	–1.45	0.034	Terf1	–2.00	0.050
Xrcc6	–5.94	0.001	Tnp1	5.90	0.011
Xrn2	–1.50	0.047	Wrnip1	–1.63	0.017
			Xpa	–1.60	0.024
			Xpc	–2.09	0.038
			Xrcc1	–2.95	0.026
			Xrcc3	–1.45	0.011
			Xrcc6	–2.61	0.032