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. 2017 May 31;58(1):115–128. doi: 10.1093/ilar/ilx011

Table 1.

NIH guide notices relating to rigor and transparency (as of October 1, 2016)

Notice number Release date Title Purpose Link
NOT-OD-15-102 June 9, 2015 Consideration of Sex as a Biological Variable in NIH-funded Research This notice focuses on NIH's expectation that scientists will account for the possible role of sex as a biological variable in vertebrate animal and human studies. http://grants.nih.gov/grants/guide/notice-files/NOT-OD-15-102.html
NOT-OD-15-103 June 9, 2015 Enhancing Reproducibility through Rigor and Transparency In this notice, the NIH Office of Extramural Research plans to clarify and revise application instructions and review criteria to enhance reproducibility of research findings through increased scientific rigor and transparency. http://grants.nih.gov/grants/guide/notice-files/NOT-OD-15-103.html
NOT-OD-16-004 October 13, 2015 NIH and AHRQ Announce Upcoming Changes to Policies, Instructions and Forms for 2016 Grant Applications This notice informs the biomedical and health services research communities of planned changes to policies, forms, and instructions for grant applications submitted in 2016. Rigor and transparency are one of several areas that the planned changes will focus on. http://grants.nih.gov/grants/guide/notice-files/NOT-OD-16-004.html
NOT-OD-16-005 October 13, 2015 NIH and AHRQ Announce Upcoming Changes to Post-Award Forms and Instructions This notice informs the biomedical and health services research communities of planned changes to policies, forms and instructions for interim and final progress reports, and other post-award documents associated the monitoring, oversight, and closeout of an award. Changes include addition of clarifying rigor language to the PHS Research Performance Progress Report. http://grants.nih.gov/grants/guide/notice-files/NOT-OD-16-005.html
NOT-OD-16-011 October 9, 2015 Implementing Rigor and Transparency in NIH and AHRQ Research Grant Applications This notice informs the biomedical research community of specific updates to application instructions and review language for research grant applications intended to enhance the reproducibility of research findings through increased scientific rigor and transparency. http://grants.nih.gov/grants/guide/notice-files/NOT-OD-16-011.html
NOT-OD-16-012 October 13, 2015 Implementing Rigor and Transparency in NIH and AHRQ Career Development Award Applications This notice informs the biomedical research community of specific updates to application instructions and review language for career development awards intended to enhance the reproducibility of research findings through increased scientific rigor and transparency. http://grants.nih.gov/grants/guide/notice-files/NOT-OD-16-012.html
NOT-OD-16-031 December 15, 2015
(Effective Date: January 25, 2016)
Updates to NIH and AHRQ Research Performance Progress Reports (RPPR) to Address Rigor and Transparency This notice informs the biomedical and health services research community of planned changes to address rigor and transparency to the PHS RPPR instructions for all annual non-competing (Type 5) NIH and AHRQ awards that support research activities. http://grants.nih.gov/grants/guide/notice-files/NOT-OD-16-031.html
NOT-OD-16-034 December 17, 2015 Advanced Notice of Coming Requirements for Formal Instruction in Rigorous Experimental Design and Transparency to Enhance Reproducibility: NIH and AHRQ Institutional Training Grants, Institutional Career Development Awards, and Individual Fellowships This notice informs the biomedical and health services research communities of NIH and AHRQ plans to require formal instruction in scientific rigor and transparency to enhance reproducibility for all individuals supported by institutional training grants, institutional career development awards, or individual fellowships. http://grants.nih.gov/grants/guide/notice-files/NOT-OD-16-034.html
NOT-OD-16-058 January 22, 2016 Reminder: NIH and AHRQ Grant Application Changes for Due Dates On or After January 25, 2016 This notice reminds the biomedical and health services research communities of announced changes to grant application policies and instructions for due dates on or after January 25, 2016. Rigor and transparency in research grant applications (including small business and complex research grant applications) are one of the areas that the planned changes will focus on. http://grants.nih.gov/grants/guide/notice-files/NOT-OD-16-058.html
NOT-OD-16-081 March 23, 2016 Reminder: NIH and AHRQ Grant Application Changes for Due Dates On or After May 25, 2016 This notice reminds the biomedical and health services research communities of announced changes to grant application policies and instructions for due dates on or after May 25, 2016. Rigor and transparency in research grant applications (including small business and complex research grant applications) are one of the areas that the planned changes will focus on. http://grants.nih.gov/grants/guide/notice-files/NOT-OD-16-081.html