Figure 3.

No effect of local resiniferatoxin (RTX) injection on burn pathology observed at 24 hours and seven days following injection. Photomicrographs of the plantar hind paw epidermis, dermis, and subcutis layers at the site of burn injury at (A) 24 hours following vehicle injection, (B) seven days following vehicle injection, (C) 24 hours following RTX injection, and (D) seven days following RTX injection. Asterisks denote plantar epithelial necrosis and denatured collagen at 24 hours followed by replacement with granulation tissue at seven days; open arrowheads denote neutrophil infiltration at 24 hours followed by multifocal neovascularization at seven days; solid arrowheads denote multifocal detachment at 24 hours followed by replacement with a serocellular crust at seven days.