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. 2016 Oct 28;18(12):2453–2465. doi: 10.1093/pm/pnw260

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2016 American Academy of Pain Medicine. This work is written by US Government employees and is in the public domain in the US.

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Resiniferatoxin (RTX) attenuates burn-evoked Fos immunoreactivity in the lumbar spinal dorsal horn one week following treatment. Photomicrographs of Fos-positive nuclei in the lumbar spinal dorsal horn at one week following a local injection of either (A) vehicle or (B) RTX in male rats at 72 hours following burn injury. (C) Photomicrograph illustrating the preabsorption control. (D) Quantification of Fos-positive cells in both vehicle-treated (open bar) and RTX-treated (solid bar) groups. * denotes significance at P < 0.05.