Table1. Thickness of the retinal layers and GCL cell count at 7 days after I/R.
Group |
Thickness (µm) |
GCL cell number (cells per 200 μm) | |||
---|---|---|---|---|---|
n=6 | Entire retina | INL | IPL | ORL | |
Sham |
144.23±3.69 |
28.42±1.92 |
27.24±1.94 |
57.24±3.61 |
17.09±1.41 |
Sham/ECH |
143.59±3.84 |
27.93±1.74 |
28.05±1.81 |
57.50±2.91 |
17.17±1.62 |
I/R/Vehicle |
100.73±3.61a* |
16.95±1.06a* |
13.01±0.92a* |
30.81±1.50a* |
7.89±0.83a* |
I/R/ECH | 126.41±3.63 b* | 21.21±1.26 b* | 23.52±1.40 b* | 46.12±4.65 b* | 12.91±1.61 b* |
Values are (means ±SE). n=6. Values compared between groups by one-way ANOVA with Dunnett’s post-test. a:compared with the Sham group; b:compared with the I/R plus vehicle group,*p<0.05 INL, inner nuclear layer; IPL, inner plexiform layer; ORL, outer retinal layers; GCL, ganglion cell layer; I/R, high intraocular pressure induced ischemia/reperfusion injury; ECH, echinacoside.