Reduced miR-17-5p expression predicts poor survival in GBM patients.
A, Representative bioluminescence images of mice bearing intracranial pCDH- or pCDH miR-17-5p-transfected N3 cells on the days indicated (n = 10 each group). B, Kaplan–Meier survival curve of mice injected with bearing pCDH- or pCDH miR-17-5p-transfected N3 cells. C, Immunohistochemical analysis of paired sections of Ki-67, CD31 and CXCL14 expression in intracranial tumours. Scale bar = 100 μm (lower). D-E, Survival analysis for miR-17-5p in TCGA (D) and CGGA (E) datasets. F-G, Univariate and multivariate analysis of gliomas in TCGA (F) and CGGA (G) datasets.