Table 1.

Association between SphK1 and clinicopathologic characteristics

Characteristics	N	SphK1 expression		χ2	P-value
		(–)	(+)
		115(32.12%)	243(67.88%)
Sex				0.022	0.883
Male	254	81(%)	173(%)
Female	104	34(%)	70(%)
Age, years				9.789	0.002**
≤55	178	71(%)	107(%)
>55	180	44(%)	136(%)
Tumor size, cm				5.393	0.020*
≤4 cm	186	70(%)	116(%)
>4 cm	172	45(%)	127(%)
Fuhrman grade				8.343	0.004**
G1–G2	297	105(%)	192(%)
G3–G4	61	10(%)	51(%)
T classification				6.895	0.006**
T1–T2	344	115(%)	229(%)
T3–T4	14	0(%)	14(%)
N classification				1.869	0.282
N0	349	114(%)	235(%)
N1	9	1(%)	8(%)
Distant metastasis				2.888	0.183
No	352	115(%)	237(%)
Yes	6	0(%)	6(%)
TNM stage				5.636	0.018*
I–II	341	114 (%)	227(%)
III–IV	17	1(%)	16(%)

*, P < 0.05; **, P < 0.01.