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. 2018 Sep 6;7(12):e1499388. doi: 10.1080/2162402X.2018.1499388

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© 2018 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

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Figure 2. — MDR1 expression in innate and adaptive immune cells in human.

MDR1 is widely expressed by immune cells from the innate (blue squares) and adaptive (red squares) compartments. MDR1 plays different role in maturation, migration and survival of the different subsets. Interestingly, it is tightly associated to specific CD4⁺ and CD8⁺ T lymphocytes subsets expressing CD161 and secreting IL-17A.