Figure 4.

Muscle-invasive bladder cancer (MIBC) subtype assignments by different gene signatures. A–C) Colorimetric chart demonstrating the distribution of MIBC patients assigned by The Cancer Genome Atlas consortium (TGCA)/MD Anderson Cancer Center (MDA)/University of North Carolina at Chapel Hill (UNC), and the tumor differentiation signatures and their relation to other signatures. D–F) The percentage of basal and differentiated MIBCs assigned by the tumor differentiation signature in the subtype assignments by the TCGA/MDA/UNC signatures in multiple cohorts of patients. MDA = MD Anderson Cancer Center; MIBC = muscle-invasive bladder cancer; TCGA = The Cancer Genome Atlas consortium; UNC = University of North Carolina at Chapel Hill.