Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Dec 3;215(12):3180–3193. doi: 10.1084/jem.20181211

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2018 Zhang et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Figure 7. — HIF1α mediates VHL-regulated type 2 responses. (A) Expression of F4/80 and CD11b among CD45⁺ cells in the lungs of control, Vhl^fl/fl LysM-Cre, and Vhl^fl/fl Hif1a^fl/fl LysM-Cre mice. (B) Expression of Spp1 mRNA in AMs. (C) Flow cytometry of CD45⁺ cells in BAL fluid and lungs of the indicated mouse strains challenged with PBS or papain. (D) Absolute numbers of CD11b⁺ CD11c⁻ SiglecF⁺ eosinophils (EOS) in BAL fluid. (E) Flow cytometry of CD45⁺ cells in lungs and BAL fluid. Numbers adjacent to outlined areas indicate percentages of Lineage⁻ CD90.2⁺ or Lineage⁻ CD90.2⁺ ST2⁺ CD44⁺ subsets. BALF, BAL fluid. (F) Absolute numbers of lung ILC2s. *, P < 0.05; **, P < 0.01; ***, P < 0.001 (Student’s t test). Data are from one experiment representative of three independent experiments (mean and SEM of three to six mice per group).