Figure 7.

B7H3 and IDO1 protein expression independently correlate with decreased survival. Kaplan-Meier curves of (A) B7-H3 and (D) IDO1 expression in osteosarcoma TMAs. Representative images of osteosarcoma tissue cores expressing (B) low levels of B7-H3, (C) high levels of B7-H3, (E) low levels of IDO1, and (F) high levels of IDO1. Low expression (red) is defined as IHC score below the mean and high expression (blue) is defined as IHC score above the mean. Statistical significance (p ≤ 0.05) was determined using both log-rank and Wilcoxon tests. Black arrows denote tumor vasculature. Scale bar = 50#181;m.