Figure 3.

UbiLT3-recognizing CD8T cells are poly-functional. 3A. Combined production of IFN-γ and TNF-α are depicted as the percentage of CD8⁺ T cells producing IFN-γ only (white bars), IFN-γ and TNF-α (black bars) or TNF-α only (striped bars). 3B. Induction of CD25 expression on CD8⁺ T cells, either or not in conjunction with IFN- γ release: IFN-γ⁺ CD25⁻ (white bars), IFN-γ⁺ CD25⁺ (black bars) or IFN-γ⁻ CD25⁺ (striped bars). 3A, B. The upper rows show data for pre-GVAX PBMC and the lower rows for post-GVAX PBMC. Duplicate wells were measured for each condition. Primary stimuli are as depicted on the x-axes and T cells were boosted using 20μg/ml UbiLT3 DRibbles.