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. Author manuscript; available in PMC: 2019 Dec 4.
Published in final edited form as: Pharmacotherapy. 2018 Jun 4:10.1002/phar.2145. doi: 10.1002/phar.2145

Figure 4. Serum MTX levels after administration of HDMTX.

Figure 4

Left panel: Figure depicts the serum methotrexate levels at 24, 48, 72, 96, and 120 hours after the administration of 100 courses of HDMTX. The x-axis is time in hours after HDMTX administration. The y-axis is MTX level, in μmol/L, shown in logarithmic scale. The red line is the median value and the black lines represent the 25th and 75th percentile values. The colored band is the range of values from minimum to maximum. The blue line is the designated limit of the toxic level at 24, 48, and 72 hours after HDMTX administration.

Right panel: Figure depicts the number of days after administration of HDMTX that >0.01 μmol/L of serum MTX remained.

HDMTX=high-dose methotrexate; MTX=methotrexate