Fig. 2.

Cytotoxicity evaluation. Cell viability in exposure to nicotinamide solution (NA), suspension of non-functionalized SLN (NF-SLN), Polysorbate80 functionalized SLN (S80-SLN), Phosphatidylserine functionalized SLN (PS-SLN), and phosphatidic acid functionalized SLN (PA-SLN). Nicotinamide amounts 1, 2 and 3 represent the equivalent amounts of 60, 30 and 15 mg NA (calculated based on the loading parameters of SLNs).^*p value <0.05 comparing to the NA solution