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. 2018 Nov 28;9:1691. doi: 10.3389/fphys.2018.01691

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Copyright © 2018 Leacy, Zouboules, Mann, Peltonen, Saran, Nysten, Nysten, Brutsaert, O’Halloran, Sherpa and Day.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Arterial blood gas and acid-base data. Ascent to high altitude (HA) had a significant effect on (A) PaO₂ (P < 0.001), (B) SaO₂ (P < 0.032), (C) PaCO₂ (P < 0.016), (D) arterial bicarbonate [HCO₃^-] (P < 0.043). Compared with baseline, ascent to HA had no significant effect on (E) base excess (P > 0.05) and (F) arterial pH (P > 0.05). ^∗ = denotes statistical significance from 1045/1400 m. † = Statistical significance from 3440 m. Presented as scatter plots representing individual participants with box and whiskers showing median, 25–75 percentile with minimum and maximum values.