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. 2018 Nov 28;9:1691. doi: 10.3389/fphys.2018.01691

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Copyright © 2018 Leacy, Zouboules, Mann, Peltonen, Saran, Nysten, Nysten, Brutsaert, O’Halloran, Sherpa and Day.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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PCAv tAUC response. Comparison of the posterior cerebral artery velocity total area under the curve (PCAv tAUC) achieved during BL and PCAv tAUC during each individual VS. Significant differences were found between BL PCAv tAUC and PCAv tAUC during VS at (A) 1045 m (P < 0.006), (B) 3440 m (P < 0.003), (C) 3820 m (P = 0.005), and (D) 4240 m (P < 0.005). ^∗ = Statistical significance from BL. † = Statistical significance from VS 1. Presented as scatter plots representing individual participants with box and whiskers showing median, 25–75 percentile with minimum and maximum values.