Table 1.
Methodological variability of 8-oxoGua, 8-oxodGuo and 8-oxoGuo measurement in human urine.
| Urine | Intra-assaya |
Inter-assaya |
|||
|---|---|---|---|---|---|
| Compounds | sample | Mean ± SD, | CVb | Mean ± SD, | CV |
| (ng/mL) | (%) | (ng/mL) | (%) | ||
| 8-oxoGua | 1 | 4.40 ± 0.11 | 2.4 | 3.85 ± 0.40 | 10.4 |
| 2 | 9.10 ± 0.26 | 2.9 | 8.87 ± 0.48 | 5.5 | |
| 3 | 14.7 ± 0.11 | 0.7 | 14.7 ± 0.11 | 0.7 | |
| 8-oxodGuo | 1 | 2.37 ± 0.09 | 3.9 | 2.21 ± 0.11 | 5.0 |
| 2 | 4.07 ± 0.06 | 1.4 | 4.06 ± 0.18 | 4.4 | |
| 3 | 9.70 ± 0.14 | 1.4 | 9.52 ± 0.35 | 3.6 | |
| 8-oxoGuo | 1 | 3.10 ± 0.42 | 13.7 | 3.01 ± 0.22 | 7.3 |
| 2 | 6.30 ± 0.50 | 8.0 | 5.91 ± 0.17 | 2.9 | |
| 3 | 11.2 ± 0.50 | 4.5 | 11.6 ± 0.35 | 3.0 | |
a
Each urine sample was analyzed six times in the intra-day and inter-day tests.
b
CV: coefficient of variation.